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Moderate association of maculopathy, high blood pressure found in large population study

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PARIS — A moderate association of high blood pressure with age-related maculopathy was found in a large population-based study involving several cities in France.

"Blood pressure has been suggested to be implicated in the etiology of ARM [age-related maculopathy]; however, epidemiological data are scarce and contradictory in this field," Jean François Korobelnik, MD, said at the Euretina meeting here preceding the European Society of Cataract and Refractive Surgeons meeting.

Most published studies rely on a single measurement of blood pressure, according to Dr. Korobelnik. The main strength of the ALIENOR (antioxydants, lipides essentiels, nutrition et maladies oculaires) study, he said, is that there was a long-term assessment of blood pressure status, which was measured over a 7-year period.

A total of 963 subjects aged 74 years or older were included.

"Hypertension was associated with a moderate increase in the risk for ARM. This association appeared similar across the different types of ARM," Dr. Korobelnik said.