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Microperimetry, fundus autofluorescence can assess outcomes of macular hole surgery

Am J Ophthalmol. 2011;151:128-136.

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Microperimetry and fundus autofluorescence can quantify the functional improvement of successful macular hole surgery, a study showed.

In the cross-sectional case series, postoperative visual acuity, microperimetry, fundus autofluorescence and spectral-domain optical coherence tomography images from 23 eyes of 23 patients were evaluated.

Researchers observed a positive correlation between the degree of fundus autofluorescence and macular sensitivity as measured by microperimetry, the study said.

All eyes had a significant decrease in fundus autofluorescence after surgery, and the decrease was found be useful in estimating the function and integrity of photoreceptors and retinal pigment epithelium after macular hole surgery.

"Moreover, functional correlation with microperimetry provides both morphologic and functional information related to repaired [macular holes]," the authors said.