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Microkeratome type may affect DLK risk, study suggests

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The type of microkeratome used for creating the LASIK flap may influence the incidence of diffuse lamellar keratitis, according to a retrospective, noncomparative study.

Pavika Thammano, MD and colleagues at Laser Eye Consultants in Boston compared the incidence of diffuse lamellar keratitis (DLK) experienced using the LSK-One and the Carriazo-Barraquer microkeratomes for flap creation. Both microkeratomes are manufactured by Moria.

The study included 1,122 consecutive LASIK cases of 584 patients. In this group of patients, there was a 2.23% overall incidence of DLK, with a statistically significant difference between microkeratome groups — 1.09% in the LSK-One microkeratome group and 4.38% in the Carriazo-Barraquer microkeratome group (P < .01).

The authors noted that epithelial irregularities also increased the risk for DLK. The incidence of DLK after Carriazo-Barraquer microkeratome use fell significantly after new cleaning methods were introduced for the device in May 2000, the authors noted.

The study is published in the Journal of Cataract and Refractive Surgery.