December 20, 2005
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Macular hole closure achieved without complete foveal tamponade during surgery

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Closure of macular holes can be achieved without complete silicone oil tamponade of the fovea during surgery, a recently published study found.

In the study, by Khami Satchi, FRCOphth, and Chetan Kantibhai Patel, FRCOphth, seven eyes of seven patients achieved closure of the macular hole after undergoing a single surgery with silicone oil tamponade. Optical coherence tomography showed that the eyes all had a silicone oil fill of more than 90%, but the silicone oil bubble in the upright position did not conform to the foveal depression.

A concentration of growth factors, adjuvants and indocyanine green in the prefoveal space may influence postoperative visual outcomes, as can changes in retinal homeostasis induced by removal of silicone oil, the study authors said.

The study is published in the December issue of Clinical & Experimental Ophthalmology.