February 16, 2011
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Lung disease not associated with early AMD


Am J Ophthalmol. 2011;151(2):375-379.

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Patients with asthma and other lung diseases do not have an associated risk of early age-related macular degeneration, a study said.

The cross-sectional Atherosclerosis Risk in Communities Study included 12,596 participants between the ages of 46 and 70 years from four communities in the United States.

Of the participants, 587 (4.7%) had early AMD, 638 (5.1%) had asthma and 581 (4.6%) had other lung diseases. A spirometer was used to assess lung function.

Researchers adjusted for age, gender, smoking and hypertension, and they found early AMD was not associated with each 1-liter increase in predicted forced expiratory volume in 1 second, forced vital capacity or peak expiratory flow rate.

In addition, forced expiratory volume in 1 second-to-forced vital capacity ratio and the presence of asthma and other lung diseases do not show a correlation to early AMD, the study said.

However, limitations included the study's cross-sectional design and the younger patient population with a lower AMD prevalence, the authors said.