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Long-standing gas tamponade better for retinal reattachment, study indicates

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A gas tamponade consisting of C₃F₈ may be effective for treating macular holes with retinal detachment, according to a Japanese study.

Riyo Uemoto and colleagues compared reattachment rates and visual acuities between 13 eyes treated with C₃F₈ gas tamponade and 12 eyes treated with SF₆ after pars plana vitrectomy. All patients had high myopia and were followed for at least 2 years.

In the vitreous cavity, C₃F₈ showed a longer half-life than SF₆. Patients treated with the C₃F₈ tamponade had a 100% anatomic reattachment rate and macular hole closure rate after the initial surgery, compared with 66.7% in the SF₆ group (P = .039). No significant differences were seen in visual acuities.

The study was published in Graefe’s Archive for Clinical and Experimental Ophthalmology.