January 18, 2005
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Light Adjustable Lens shows ‘precise adjustment’ at 24 months, data show

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WAIKOLOA, Hawaii — The Light Adjustable Lens has been shown to allow “precise adjustment” in the eye with follow-up now reaching 24 months, according to one of the lens’s investigators.

Daniel M. Schwartz, MD, described preliminary results with Calhoun Vision’s Light Adjustable Lens (LAL) here at Hawaii 2005, The Royal Hawaiian Eye Meeting. He said the clinical study set out to determine whether the foldable silicone LAL can undergo precise adjustment of spherical and astigmatic power in the eye.

Adjustment of spherical refractive error of 1.5 D to –1.25 D was achieved in 12 patients, Dr. Schwartz said. He explained that all the achieved power changes were within 0.25 D of the attempted values, with the exception of one patient who was within 0.5 D. Additionally, astigmatic correction of 0.75 D was achieved in one patient. The patient’s uncorrected visual acuity improved from 20/30 to 20/20 after the adjustment.

Dr. Schwartz said that all patients maintained their pre-adjustment best corrected visual acuity.

He said Calhoun Vision partnered with Carl Zeiss Meditec in 2004 to make a digital light delivery device for use in lens adjustment. He said the device uses 1.3 million mirrors that move 1,000 times per second.

“We can correct not just simple refractive error, but also higher-order aberrations,” he said.

He added that when the LAL was being developed, it was not clear whether the lens would remain biocompatible after the light treatment. Since the lens has been used clinically, he said, investigators have found that it remains biocompatible after the light device is used.