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Lens opacification with phakic IOL correlated with older age, lower cell density

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The risk factors for lens opacification after implantation of STAAR Surgical’s ICL include intraoperative trauma, older age and reduced endothelial cell density, according to a prospective study.

Birgit Lackner, MD, and colleagues at the University of Vienna Medical School implanted the ICL (since renamed the Visian ICL) into 76 eyes of patients with myopia. Patients were evaluated preoperatively and at 1, 3, 6, 12, 24 and 36 months. Both uncorrected and best corrected visual acuity were determined. Eyes that developed opacification were followed for at least 12 months.

Lens opacification occurred in 11 eyes (14.5%), and it was correlated with intraoperative trauma to the crystalline lens, age older than 50 years at the time of surgery and the decrease of endothelial cell density values throughout the observation period. ICL vaulting was not correlated with lens opacification risk.

Of the 11 eyes, five (55%) had progressive opacification, losing between 3.5 and 0.5 lines. Three of the eyes with progressive opacification had a one- or two-line loss of BCVA from preoperative values and subsequently underwent cataract surgery.

The study is published in the November issue of Journal of Cataract & Refractive Surgery.