Latanoprost lowered diurnal IOP in normal-tension glaucoma patients, study finds
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Latanoprost significantly reduced IOP throughout the day and night in patients with normal-tension glaucoma without their affecting blood pressure or ocular perfusion pressure, a study found.
Toshiaki Kubota, MD, PhD, of the University of Occupational and Environmental Health in Kitakyushu, Japan, and colleagues evaluated the efficacy of Xalatan (latanoprost 0.005%, Pfizer) in controlling diurnal variations in IOP in 22 eyes of 22 patients with normal-tension glaucoma.
After 3 months of daily treatment, latanoprost produced a significant (P < .001) decrease in IOP at all time points measured over 24 hours but did not significantly affect blood pressure or ocular perfusion pressure compared to baselines levels, according to the study.
The study is published in the October issue of the Journal of Glaucoma.