June 04, 2007
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LASIK may alter anterior chamber depth, angular aperture, study suggests

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CANCUN, Mexico — Both conventional and customized LASIK cause changes in angular aperture and anterior chamber depth, according to an ophthalmologist speaking here at the Pan-American Association of Ophthalmology meeting.

Narlly Ruiz Quintero, MD, presented the results from a prospective, longitudinal, descriptive study of 80 patients treated with LASIK in both eyes; 40 patients received conventional ablations and 40 received customized LASIK.

In all cases, Dr. Quintero targeted ablation depths of more than 90 µm, she said.

Angular apertures were measured at 1 month and 16 months postop using ultrasound biomicroscopy.

Among patients in the customized LASIK group, anterior chamber depths averaged 3.19 mm preoperatively and decreased to 3.08 mm at 1-month follow-up. Angular apertures significantly decreased in three meridians, Dr. Quintero said.

Anterior chamber depths averaged 3.14 mm preoperatively for patients in the conventional LASIK group and decreased to 3.09 mm at 1-month follow-up. Angular apertures significantly decreased, but only in one meridian, she said.

"These statistically significant changes at 1 month remained without change up to the 16-month follow-up," Dr. Quintero said, noting that the changes were more evident among patients in the customized LASIK group.