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Iris-fixation of IOL during corneal transplant shows good results

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Implantation of an iris-supported posterior chamber IOL during penetrating keratoplasty can provide adequate vision with an acceptable complication rate, according to a large retrospective study.

Ayad A. Farjo, MD, and colleagues at several institutions in the United States reviewed the records of 366 eyes of 342 patients who underwent PK over a 9-year period, mainly for pseudophakic and aphakic bullous keratopathy. All patients received iris-sutured posterior chamber IOLs at the time of PK and were followed for a mean of 3 years.

Best corrected visual acuity significantly improved from an average of 20/474 preoperatively to 20/85 at 1 year follow-up (P < .0001).

Nine eyes (7.7%) with preoperative glaucoma required increased therapy to control IOP, and 72 eyes (29%) without preoperative glaucoma required treatment for postoperative increases in IOP. The researchers also identified 79 eyes (28%) with previously undiagnosed cystoid macular edema.

According to the study authors, 36 eyes (9.8%) experienced graft rejection episodes, and 27 eyes (7.4%) had a known graft failure by final follow-up. Two eyes (0.5%) required enucleation after wound disruption.

The study was published in the journal Cornea.