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IOP-lowering effect same for laser suture lysis, adjustable sutures

J Glaucoma. 2011;20(4):228-233.

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When comparing adjustable sutures and laser suture lysis after trabeculectomy in glaucomatous eyes, there was no significant difference in hypotensive efficacy, a study found.

Fifty eyes with primary open-angle glaucoma and IOP of at least 22 mm Hg were randomly assigned to trabeculectomy with mitomycin C and adjustable sutures or trabeculectomy with conventional sutures and laser suture lysis. A single surgeon preformed all the surgeries.

IOP was measured with Goldmann applanation tonometer. Measurements of each eye were obtained at 1 and 3 days, 1 and 2 weeks, and 1, 2, 3, 4, 5, 6, 9 and 12 months. These calculations were compared with measurements obtained 2 weeks before the surgery. Statistically significant reductions in IOP were found at all visits for both groups (P < 0.0001). After 12 months, mean IOP difference was -15 ± 4.7 mm Hg in the adjustable suture group and -13. 5 ± 4.4 mm Hg in the laser suture lysis group.

The study authors noted the small sample size as a limitation and recommended that their observations be verified in a larger population.