October 07, 2002
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IOP-induced interlamellar stromal keratitis: early recognition

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ALBANY, N.Y. — Elevated intraocular-induced post-LASIK interface keratitis is a poorly documented phenomena that may be caused by or worsened by frequent topical steroids, according to a study. Early recognition of the disease is important, authors caution.

Michael W. Belin, MD, and colleagues reviewed medical records from four LASIK patients diagnosed with IOP-induced interface changes.

Slit-lamp findings and visual degradation appeared identical to diffuse lamellar keratitis. However, all cases presented outside the first week and were not associated with any antecedent trauma. All cases failed to respond to high-dose topical steroids. Significant IOP elevations were noted in all cases, according to the authors.

The authors also noted that interface changes responded dramatically to both a lowering of IOP and a discontinuation or lowering of the topical steroids.

The study is published in the October issue of Ophthalmology.