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IOP in fellow eye may remain relatively unchanged after trabeculectomy

Ophthalmic Surg Lasers Imaging. 2011;42(2):138-143.

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IOP of the fellow untreated eye may go largely unchanged after uncomplicated trabeculectomy, a study found.

The retrospective consecutive case series assessed the preoperative and postoperative IOP of 61 patients who underwent unilateral trabeculectomy. Pressure was monitored up to 3 months postop.

IOP in the fellow eye was unchanged at all follow-up examinations, except on postop day 4 when it significantly decreased. The reduction was correlated with the eye's central corneal thickness, as well as the amount of IOP reduction in the operated eye.

The study authors believe the delayed timing of this IOP decrease may be due to the build-up of a vasogenic or neurocrine feedback response derived from changes in the operated eye.

They also suggested that the inverse correlation between IOP and corneal thickness may imply that eyes with low corneal thickness are more susceptible to stimuli that mediate IOP reduction.