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IOLs in the pipeline include accommodating, photochromic designs
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WAILEA, Hawaii — For several IOLs currently in development in the United States, “the story … is still unfolding,” according to I. Howard Fine, MD.
Dr. Fine gave an update on IOLs in the pipeline in a presentation here at Hawaiian Eye 2006. The IOLs in development employ new accommodative mechanisms, photochromic capabilities and other innovative characteristics, he said.
In clinical trials of the Visiogen Synchrony dual-optic accommodating IOL, Dr. Fine said, 100% of 24 eyes had best corrected visual acuity of 20/40 or better at 6 months postoperative, according to data from Visiogen.
Another accommodating design, a deformable IOL from Power Vision, incorporates “new applied microfluidic technology in a single-piece IOL with a ‘dynamic optic,’” Dr. Fine said. When the lens is in place in the eye, microfluidic pumps “reversibly alter the radius of the curvature and effect an increase in IOL power for near vision,” he said.
Dr. Fine also discussed the LiquiLens from Vision Solution Technologies, yet another approach to pseudoaccommodation. Dr. Fine said this device “will provide emmetropia at distance and an accommodative mechanism that allows the lens to achieve three times and above magnification for near.” He said this lens, which is still in the prototype stage, functions based on gravity, and “is the only lens that functions in this way.”
Also under investigation is the Photochromatic Matrix IOL from Medennium. Dr. Fine said in dim-light conditions, this lens behaves like an ultraviolet-blocking IOL.
“Only in photopic conditions does it turn yellow and block blue light,” he said.