October 21, 2010
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Iodine iontophoresis may aid eye in defense against environmental oxidative stress

Graefes Arch Clin Exp Ophthalmol. 2010;248(11):1639-1646.

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Iodine iontophoresis appears to increase the antioxidative capacity of the tear fluid, which may, in turn, act as a defense mechanism against the development of dry eye in response to environmental oxidative stress, according to a study.

A prospective evaluation of 92 patients found that iodine iontophoresis increased antioxidative capacity of the tear fluid in the 24 patients treated; however, water-soluble antioxidative capacity was not increased in serum samples taken from those patients.

In a group of 25 patients treated with both iodine iontophoresis and balneotherapeutic methods, the water-soluble antioxidative capacity was increased in the serum but not in the tear film. Iodine excretion was increased in urine samples from both groups treated with iodine iontophoresis, as well as in samples from a group of 24 patients treated with balneotherapeutic methods only, when compared with a group of 21 patients followed as controls.