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Increased IOP is modifiable risk factor for OAG, study finds
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While nonmodifiable risk factors may be used to identify people at a high risk of developing open-angle glaucoma, increased intraocular pressure is an important modifiable risk factor, according to a 5-year, population-based study.
Anhchuong Le and colleagues at the Centre for Eye Research Australia interviewed and examined 3,271 participants from nine urban areas at baseline and at 5-year follow-up. Potential risk factors for developing OAG were identified.
Increased age and increased IOP were associated with an increased risk of development of OAG. Family history of glaucoma, the presence of age-related macular degeneration, the presence of pseudoexfoliation and a cup-disc ratio greater than 0.7 were associated with greater risk of development of at least possible OAG. Participants who took beta-blockers and participants with a cup-disc ratio higher than 0.7 were at significant risk for developing at least probable OAG.
The study is published in the September issue of Investigative Ophthalmology & Visual Science.