This article is more than 5 years old. Information may no longer be current.
Hydrogel adhesive more effective than suture for incision closure in animal study
Click Here to Manage Email Alerts
Corneal incisions of up to 5 mm were sealed better with a hydrogel tissue adhesive than with suturing, according to a rabbit study.
Defne Kalayc, MD, and others at Boston’s Schepens Eye Institute created through-and-through central linear corneal incisions of between 1 mm and 5 mm length in enucleated rabbit eyes. As controls, the leaking pressures were measured immediately after the incisions were made. In half the eyes, incisions were sealed with hydrogel adhesive, and the other half were sutured with 10-0 nylon.
The differences in the leaking pressures before and after adhesive application were higher than the differences before and after suturing. With the exception of the 1 mm incision group, all differences were statistically significant.
The study is published in the June issue of Ophthalmic Research.