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High myopia not a factor in posterior capsule opacification, study finds

J Cataract Refract Surg. 2009;35(9):1532-1539.

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High axial myopia does not appear to be a factor in posterior capsule opacification in patients who receive a single-piece acrylic IOL, according to a study.

Because high myopia is a risk factor for cataract development, the investigators speculated that high myopia might also influence the development of posterior capsule opacification.

However, rates of posterior capsule opacification were not significantly different at any time point in eyes with an axial length of 26 mm or more that underwent phacoemulsification and received an Alcon AcrySof IOL compared with eyes with an axial length between 21 mm and 23.99 mm that underwent the same operation.

At 1 month, median posterior capsule opacification was 3.2% in the high myopia group compared with 5.6% in the comparator group; at 12 months, 2.2% vs. 1.6%; at 24 months, 7% vs. 2.3%; at 36 months, 3.7% vs. 3.6%; and at 48 months, 10% vs. 2.3%.

At 4 years after the time of surgery, posterior capsule opacification was visible in the central 3 mm of the IOL in 38% of myopic eyes compared with 20% in the comparison group (P = .04).