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Glaucoma diagnostic testing tool shows progression, reproducibility in some cases
Ophthalmology. 2010;117(4):724-729.
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The Heidelberg Retina Tomograph Glaucoma Probability Score effectively measures glaucoma progression, with better reproducibility in extreme results than mid-range, a study found.
"Changes in HRT GPS values between 0.30 and 0.78 should be interpreted with caution because the index has poorer reproducibility in this range," the study authors said. "The global GPS progression algorithm performs at least as well as previously described rim area-based HRT progression strategies."
The randomized, controlled clinical trial examined diagnostic testing of 43 ocular hypertension subjects and 31 glaucoma subjects for reproducibility, and 198 ocular hypertension subjects and 21 control subjects for progression.
When examining reproducibility, global Glaucoma Probability Score (GPS) values were created for HRT images from testing and retesting, obtained by two observers at two visits within 6 weeks. When examining progression, GPS values were created for HRT images taken from 1993 to 2001.
According to the study, the GPS found that 25 ocular hypertension subjects progressed. Of those, 11 also progressed by visual field measurement, with 26 total subjects progressing only by visual field.
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