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Fixed-combination drugs a compelling proposition in glaucoma therapy, clinician says
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BERLIN — More controlled studies must be performed to establish efficacy of fixed-combination medications for glaucoma treatment, a clinician said here.
 Anastasios Konstas |
"Fixed combinations ... do work in real-life practice by keeping medical therapy practicable. I think that fixed combinations are a compelling proposition in the management of glaucoma. I think that they provide important benefits in most patients ... especially in real-life practice," Anastasios Konstas, MD, PhD, said here at the World Ophthalmology Congress. "But we still need to see controlled evidence in the future to prove the clinical advantages."
Dr. Konstas recommended that physicians not compare fixed combinations and monotherapy agents. He said it is more helpful to regard adjunctive therapy separately or together.
He said fixed therapy has been shown in other medical fields to decrease rates of non-adherence. Fixed combination drugs also offer fewer bottles needed for glaucoma therapy and less potential for toxicity from preservative exposure.
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