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FDT advantageous in classifying glaucoma patients

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ERLANGEN, Germany — Frequency-doubling perimetry can help classify and detect “a considerable proportion” of glaucomatous patients, according to a study here.

Researchers here used conventional perimetry and frequency-doubling perimetry (FDT) to evaluate 173 eyes with ocular hypertension, 116 eyes with glaucomatous disc damage but no defects on standard visual field testing (“preperimetric” eyes), 199 eyes with disc damage and field defects (“perimetric” eyes) and 151 control eyes.

Four repeated measurements with FDT were carried out on 15 glaucoma patients at 2 hour intervals to judge reproducibility at test locations. Considerable variation was found at single test points.

Despite this variation, the number of missed test stimuli with FDT was significantly correlated with corresponding visual field defects (P < .001), the researchers said. The FDT classified as glaucomatous 11% of ocular hypertensive eyes, 28.5% of preperimetric glaucoma eyes and 87% of perimetric glaucoma eyes.

The study is published in Graefe's Archive for Clinical and Experimental Ophthalmology.