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Eyes with damage to both hemifields show fastest glaucoma progression
Arch Ophthalmol. 2009;127(9):1129-1134.
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Patients with initial superior defect and initial inferior defect did not experience glaucoma progression as quickly as those who had damage to both hemifields, a study found.
"Initial damage to both hemifields increases the risk of glaucoma progression. More aggressive therapy should be considered for these eyes," the authors said.
The study looked at 205 eyes of 205 patients with glaucomatous optic neuropathy, 10 or more Swedish Interactive Threshold Algorithm standard 24-2 visual fields taken over at least 5 years, and a mean deviation smaller than –6.0 dB from a review of 43,660 medical records.
Three patient groups were formed: Group A had 79 patients with initial superior defect; group B had 61 patients with initial inferior defect; and group C had 65 patients with both hemifields affected.
Mean follow-up was 6.5 years.
The researchers found that group C had the most rapid glaucoma progression (P < .02). On multivariate analysis, they also found significant impact of higher baseline IOP and thinner central corneal thickness.