This article is more than 5 years old. Information may no longer be current.

Endothelial cell loss remains stable 2 years after DSAEK

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

FORT LAUDERDALE, Fla. — Patients with Fuchs' endothelial dystrophy who underwent Descemet's stripping automated endothelial keratoplasty had relatively stable endothelial cell loss up to 2 years postoperatively, according to a poster presented here.

Jennifer Y. Li, MD, and colleagues reported results from the prospective, noncomparative, interventional case series at the Association for Research in Vision and Ophthalmology meeting.

The study included 439 eyes undergoing DSAEK for Fuchs' endothelial dystrophy. Donor endothelial cell density (ECD) was measured at 4 years postoperatively in 36 eyes and compared with preoperative eye bank measurements. Donor ECD was also measured at 3 years in 115 eyes, at 2 years in 230 eyes, at 12 months in 360 eyes and at 6 months in 439 eyes.

At 6 months, the average ECD loss was 24.9 cells/mm² ± 16.1%; at 12 months, the average ECD loss was 25.0 cells/mm² ± 16.1%; at 2 years, the average ECD loss was 25.7 cells/mm² ± 16.6%.

After 2 years, researchers observed a gradual decline in ECD.

• Disclosure: No products or companies are mentioned that would require financial disclosure.