Endoscopic goniotomy lowers IOP in some primary congenital, developmental glaucoma cases
J Glaucoma. 2010;19(4):264-269.
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A small pilot study examining endoscopic goniotomy found that success was achieved after the procedure in less than half of children with opaque corneas and primary congenital glaucoma or developmental glaucoma.
"On average, [endoscopic goniotomy] lowered IOP by 16.7 mm Hg from preoperative baseline to the last follow-up visit in the 16 eyes, which constituted about 46% reduction from baseline IOP," the study authors said.
The retrospective review looked at 16 eyes of eight patients, four with primary congenital glaucoma, two with aniridia, one with Rubinstein-Taybi syndrome and one with neurofibromatosis. All patients underwent endoscopic goniotomy "for approximately 300° of the angle through temporal and superonasal corneal incisions." Mean age was 3.81 months.
Cases were consecutive, with an average follow-up of 18.8 months. The study's main outcome measurement was IOP change from baseline. Success was IOP of 21 mm Hg or less with or without medications and no further surgery.
The study found that six eyes achieved success. Additional surgery was required in three patients. The most common complication was transient hyphema in eight eyes.
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