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Electron beam radiation therapy may be viable approach to failed squamous cell carcinoma treatments
Ophthal Plast Reconstr Surg. 2011;27(4):227-281.
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A study reported successful local tumor control using electron beam radiation therapy for recalcitrant squamous cell carcinoma.
The retrospective study examined data from a small case series of eight patients diagnosed with squamous cell carcinoma who had failed standard treatment therapies. Six patients were men, and two were women; mean age was 50 years. Mean follow-up after electron beam radiation therapy was 30.25 months.
Tumor control and regression occurred in six of the patients. No metastatic spread or tumor-related deaths were reported. Erythema and edema of the eyelids with diffuse transient eyelash loss were the most prevalent side effects. Two patients had tumor recurrence.
"Though this is a small case series and more long-term follow-up is needed to assess late-term morbidity, we have found no side effects that might preclude the use of [electron beam radiation therapy] for recalcitrant [squamous cell carcinoma]," the study authors said.