October 09, 2006
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Early vitrectomy, lensectomy may prevent retinal detachment in ROP cases

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Early vitrectomy and lensectomy may help prevent retinal detachment in children with aggressive fibrovascular proliferation in posterior retinopathy of prematurity, a Japanese study found.

Noriyuki Azuma, MD, PhD, of the National Center for Child Health and Development, Tokyo, and colleagues reviewed the results in 22 eyes of 15 children treated with vitrectomy for aggressive posterior ROP. In all children, fibrovascular proliferation had progressed unabated despite early, dense retinal photocoagulation and early re-treatment, according to the study.

Vitrectomy with lensectomy was performed in 16 of the 22 eyes and lens-sparing vitrectomy in six eyes.

At 9 months mean follow-up, all eyes that underwent vitrectomy plus lensectomy achieved retinal reattachment, 56% achieved foveal configuration and 88% achieved steady fixation, according to the study.

In contrast, the six eyes treated with lens-sparing vitrectomy developed large tractional retinal detachments by 9 months mean follow-up, the authors said.

The study is published in the October issue of the American Journal of Ophthalmology.