This article is more than 5 years old. Information may no longer be current.

Early pre-plus ROP may be linked to development of severe disease

Arch Ophthalmol. 2011;129(5):591-596.

Add topic to email alerts

Receive an email when new articles are posted on

Please provide your email address to receive an email when new articles are posted on .

Subscribe

Added to email alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

You've successfully added to your alerts. You will receive an email when new content is published.

Click Here to Manage Email Alerts

Back to Healio

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com.

Back to Healio

Pre-plus retinopathy of prematurity that presents early may be strongly correlated with development of severe disease and a need for laser treatment, a prospective study demonstrated.

Two masked experts observed posterior retinal video recordings of 214 premature infants from 710 examinations conducted over a span of 5 years, classifying ROP as plus, pre-plus or neither.

Of 10 eyes with pre-plus disease at 33 to 34 weeks' postmenstrual age, 70% required laser surgery, while only 9% of 154 eyes with neither pre-plus nor plus disease required such treatment.

After adjusting for birth weight, gestational age, ROP location and disease severity, pre-plus disease at 33 to 34 weeks' postmenstrual age independently predicted the need for laser intervention. Mean time between diagnosis and treatment was 1.6 weeks.