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Dye did not improve results of macular hole surgery

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Use of indocyanine green staining did not affect the long-term outcomes of macular hole surgery, a study found.

Kazuyuki Kumagai, MD, and colleagues conducted a retrospective, nonrandomized study of 190 cases in 182 patients to evaluate indocyanine green (ICG) as a staining agent during internal limiting membrane peeling. Surgeons performed 94 procedures without using the dye. Another 96 cases were completed using an intravitreal application of 0.1 mL to 0.2 mL of 0.1% ICG solution.

Follow-up averaged 30.7 months for non-stained patients and 26.2 months for ICG-stained patients. At final follow-up, the researchers found that 99% of cases in both groups had achieved anatomic macular hole closure. Patients in both groups also experienced similar significant improvements in visual acuity, according to the study.

The study is published in the July/August 2006 issue of Retina.