June 10, 2004
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Dry eyes show more aberrations in wavefront study

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Greater optical aberrations, especially higher-order aberrations, were seen in the eyes of patients with dry eye than in normal control eyes, according to a study. The increase in higher-order aberrations resulted from increased tear film irregularity, the study’s authors suggested.

Robert Montés-Micó, OD, MPhil, and colleagues at the Ophthalmologic Institute of Alicante, Spain, performed wavefront analysis of higher-order aberrations in 20 eyes with dry eye syndrome and 20 healthy eyes. The average age of people with dry eye was 27.5 years and the average age of the healthy subjects was 26.3 years.

In both 4-mm and 6-mm diameter pupil measurements, total aberrations were significantly greater in dry eyes than in normal controls. This included both spherical-like and coma-like aberrations. The researchers said this suggests that tear film changes in dry eyes lead to irregularities on the corneal surface.

The study is published in the May/June issue of Journal of Refractive Surgery.