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‘Double filling’ reduces emulsification
Combined use of perfluorohexyloctane and silicone oil as an intraocular tamponade is more effective than using silicone oil alone, according to an Italian study.
Luciano Lepori and colleagues in Pisa mixed perfluorohexyloctane and silicone oil to determine if the combination was better than its components alone as a tamponade.
They found the mixing process to be slow, with equilibrium reached after 1 month. The final ratio of the double filling phases differs from the initial ratio, the authors said.
Before being mixed, perfluorohexyloctane “was found to show close contact with the eye model and dispersion into droplets,” they said. They added that the silicone oil “showed poor contact with the cell surface and no dispersion.”
When compared with using just the perfluorohexyloctane, the double filling mixture reduced emulsification, they said.
The study is published in the January issue of Graefe’s Archive for Clinical and Experimental Ophthalmology.