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Disc edema has effect on OCT measurements, study finds

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Optical coherence tomography measurements are influenced by disc edema and are higher in patients with disc edema than in healthy eyes, according to a study.

Marcel N. Menke and colleagues at the Schepens Retina Associates Foundation in Boston studied 13 patients with disc edema and compared them to 13 patients with healthy eyes. Of the 13 patients with disc edema, seven presented with retinal vein occlusions and six had inflammatory optic neuropathy. Retinal nerve fiber layer (RNFL) thickness circle scans centered on the optic disc were made for all patients. The same circle scans were also used for peripapillary total retinal thickness measurements. The RNFL percentage of total retinal thickness was calculated, normalized and averaged separately for both affected and unaffected regions in the eyes.

For eyes with disc edema, the average RNFL thickness was 122 µm; it was 91 µm for the control eyes (P = .0001). The mean peripapillary total retinal thickness was 329 µm in the eyes with disc edema and 255 µm in the healthy eyes (P < .001).

The study is published in the October issue of Investigative Ophthalmology & Visual Science.