August 17, 2005
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Diode laser cycloablation can control silicone-oil-induced IOP increases

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Diode laser cyclophotocoagulation can help control silicone-oil-induced IOP elevation when medication fails to do so, according to a study. It appears that IOP can be controlled over the long term, the study authors said.

S.M.S. Ghazi-Nouri and colleagues at Moorfields Eye Hospital in London reviewed the charts of 38 patients who underwent cyclodiode treatment following injection of silicone oil over a 10-year period. Patients were followed for 13 to 113 months.

Seventeen of the patients had silicone oil still in place at the time of their first laser treatment. The mean pretreatment IOP was 31.4 mm Hg, falling to 18.6 mm Hg at 1 year and to 13.9 mm Hg at final follow-up visit. Before treatment, 28 patients were on two or more topical medications, and this number was reduced to 18 at 1 year and to 13 at final follow-up visit. Use of oral acetazolamide was also reduced, from 16 patients pre-laser to five at 1 year and three at final visit.

Four patients at 1 year and five patients at the final visit had hypotony; one patient needed enucleation 75 months after the first cyclodiode treatment.

The study is published in Eye.