March 05, 2003
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Differential diagnosis limited with sectorial keratitis, uveitis

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BOSTON — The differential diagnosis of uveitis and sectorial keratitis is limited and the entities included diverse, according to a comparative study. Ophthalmologists are encouraged to be familiar with the various entities to ensure proper disease management, authors said.

C. Stephen Foster, MD, and others here at the Massachusetts Eye and Ear Infirmary retrospectively reviewed data on six patients with both sectorial keratitis and uveitis. Patients ranged in age from 21 to 50 years; four were female, two were male. All patients were eventually diagnosed with herpes simplex viral stromal sectorial keratitis.

Five of the six patients were successfully treated with topical steroids and antiviral treatments. One patient required methotrexate, cyclosporine and systemic prednisone as treatment. Six of seven eyes had glaucoma. Five patients also developed corneal scarring.

The study is published in the February issue of Graefe’s Archive of Clinical and Experimental Ophthalmology.