December 09, 2004
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Diabetic macular edema can resolve quickly after intravitreal steroid injection

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Total resolution of diabetic macular edema occurred as early as 1 week after intravitreal steroid injection in a small case series recently reported.

M.S. Islam and colleagues at Queens Medical Centre in Nottingham, England, treated seven phakic eyes of seven patients with diabetes, previously diagnosed with clinically significant macular edema, with a single 4-mg intravitreal injection of triamcinolone acetonide. The eyes were assessed with optical coherence tomography before and 1 week after the injection.

Mean improvement in reading ability was three lines at 1 week after injection. Mean improvement in logMAR best corrected visual acuity was 0.146 (P = .03). The mean reduction in central macular thickness was 150.9 µm at 1 week (P = .02).

The study is published in Eye.