This article is more than 5 years old. Information may no longer be current.
Deep sclerectomy with deroofing of Schlemm's canal, MMC effective in primary open-angle glaucoma
Click Here to Manage Email Alerts
Performing nonpenetrating deep sclerectomy with deroofing of Schlemm's canal and mitomycin-C appears safe and effective for treating primary open-angle glaucoma, according to a prospective study by researchers in India.
Priyanka Sharma and colleagues investigated the efficacy of nonpenetrating deep sclerectomy with Schlemm's canal deroofing and intraoperative MMC in 33 eyes of 33 newly diagnosed primary open-angle glaucoma patients. They published their results in the June issue of Asian Journal of Ophthalmology.
The researchers conducted follow-up at 1 and 5 days postop, at 1 month and every 3 months thereafter. They defined successful surgery as an IOP of 21 mm Hg or less and a 30% IOP reduction or more without medication, according to the study.
At 15 months postop, 96.9% of the procedures were considered successful, the authors reported.
In addition, the patients' visual acuity remained stable, and there were no significant changes in anterior chamber depth.
However, microperforations occurred in 9% of the patients, shallow dissection in 3%, bleb region hemorrhaging in 9% and conjunctival wound gape without leak in 6%, according to the study.