August 25, 2006
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Deep sclerectomy beneficial in pseudoexfoliative glaucoma

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Deep sclerectomy with an implant may be more effective in patients with pseudoexfoliative glaucoma than in patients with primary open-angle glaucoma, a study suggests.

Liv Drolsum, MD, of Ullevaal University Hospital, Norway, compared the long-term results of deep sclerectomy with implant in 28 consecutive pseudoexfoliative glaucoma patients and 27 patients with primary open-angle glaucoma. At a mean follow-up of 45 months, 50% of the patients with pseudoexfoliative glaucoma had achieved "complete success," defined as IOP of less than 19 mm Hg without additional medication. In the patients with primary open-angle glaucoma, 33.3% achieved complete success at a mean 43 months' follow-up, according to the study.

At 4 years follow-up, patients in the pseudoexfoliative glaucoma group had an average IOP of 15.5 mm Hg and used an average of 1.7 medications per patient. Patients in the primary open-angle glaucoma group had a mean IOP of 13.6 mm Hg and used an average of 1.2 medications per patient, according to the study.

The study is published in the August issue of Acta Ophthalmologica Scadinavica.