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Decreased anterior chamber angle predictive of glaucoma progression after laser peripheral iridotomy

J Glaucoma. 2009;18(7):521-527.

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After laser peripheral iridotomy, some primary angle closure suspects progressed to primary angle closure, and of that group, the majority had decreasing anterior chamber angle, a study found.

The study examined 82 eyes of 82 primary angle closure suspects of Asian Indian origin. Subjects had A-scan biometry and ultrasound biomicroscopy at a tertiary eye hospital. Measurements including anterior chamber depth, anterior chamber angle and axial length were taken before and after laser peripheral iridotomy.

At 2 years follow-up, 15 of 52 eyes progressed to primary-angle closure. Narrow angle, ultrasound biomicroscopy parameters, vertical cup-to-disc ratio, age and sex were not predictive factors for developing the disease, the study authors said. Decreasing anterior chamber angle, however, was a significant risk factor.

IOP did not increase after laser peripheral iridotomy.