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Cystoid macular edema, hypotony are most significant complications in childhood uveitis
Ophthalmology. 2009;116(8):1544-1551.
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A study examining disease characteristics and visual results of children with uveitis found that complications were prevalent.
"The rate and spectrum of vision-threatening complications of pediatric uveitis are significant," the study authors said.
The retrospective, longitudinal observation was conducted with 527 patients who had pediatric uveitis. At diagnosis, the median patient age was 9.4 years. Follow-up was up to 10 years, with examinations at 1-, 3- and 5-year time points.
Complications happened often in the cases. Adverse events with the most significant visual impact were cystoid macular edema (P = .006) and hypotony (P = .026).
Prevalence of legal blindness at baseline was 9.23%; at 1 year, 6.52%; at 3 years, 3.17%; at 5 years, 15.15%; and at 10 years, 7.69%.
"Posterior uveitis and panuveitis had more severe vision loss," the authors said. "Hispanic ethnicity was associated with a higher prevalence of infectious uveitis and vision loss at baseline."