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Cyclodiode therapy ‘highly effective’ but runs hypotony risk

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For patients undergoing surgical treatment for refractory glaucoma, cyclodiode therapy is an effective treatment option but has a significant risk of hypotony associated with it, according to a study.

J.P. Diamond and colleagues at Bristol Eye Hospital in England analyzed 263 eyes of 238 patients who underwent transscleral diode laser cyclophotocoagulation. Mean intraocular pressure decreased significantly from 40.7 mm Hg before cyclodiode therapy to 17.7 mm Hg after treatment. Hypotony occurred in 9.5% of patients, 76% of whom had neovascular glaucoma.

Treatment failure was associated with male sex and a low mean energy per treatment session. High pretreatment IOP and a high mean energy per treatment episode appeared to be associated with the occurrence of hypotony.

The study is published in the October issue of British Journal of Ophthalmology.