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Cup-to-disc ratio, refractive error affected in nonarteritic anterior ischemic optic neuropathy patients.
Ophthalmology. 2008;115(12):2275-2281.
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A higher degree of myopia and hyperopia was associated with larger cup-to-disc ratio in patients with anterior ischemic optic neuropathy. Overall, cup-to-disc ratio in those patients was significantly smaller than in the general population.
Researchers conducted a cohort study of 608 consecutive patients with nonarteritic anterior ischemic optic neuropathy, with a mean age of 60.9 years. Patients received a comprehensive ophthalmic evaluation. Morphometric measurement of cup-to-disc ratio was taken in 65 normal eyes in patients with unilateral nonanterior ischemic optic neuropathy.
Clinicians found a significant association between spherical equivalent refraction and age; emmetropia prevalence decreased with age, while hyperopia prevalence increased.
"Comparison with the age-matched U.S. population from the 1999-2000 National Health and Nutrition Examination Survey showed a higher proportion of [nonanterior ischemic optic neuropathy] eyes with spherical equivalent from –0.5 to 0.5 D and a smaller proportion with –3 to less than -0.5 and less than 0.5 to +3 D (P < .001)," study authors said.
They also found that not having a small cup was a secondary factor in the development of nonanterior ischemic optic neuropathy.