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Cross-linking research has come a long way, speaker says
CHICAGO — Multiple lines of research investigating new uses of cross-linking in the eye are contributing to an ever-growing stock of data surrounding the procedure, according to a speaker here.
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"Cross-linking is ... becoming a clinically accepted procedure," Theo Seiler, MD, PhD, said during the Charles D. Kelman Innovator's Lecture at the Innovators Session of the American Society of Cataract and Refractive Surgery annual meeting.
"Whenever you put something in, next door, the guys are starting to change the idea to include something new and to expand it, and that's exactly what's happened here in the last 2 years," Dr. Seiler said.
Current investigations are looking at performing PRK in cross-linked eyes and performing scleral cross-linking, he said.
Several investigators are also looking at performing cross-linking after LASIK keratectasia. Dr. Seiler presented a study of 10 such cases, in which the condition developed an average of 8.5 months after surgery.
Progression of keratectasia was stopped in all cases after cross-linking. Six patients had an improvement in best corrected visual acuity of more than two lines, while no patients lost more than two lines of BCVA. Uncorrected visual acuity also improved by more than two lines in three patients.
At this point, "we do not have a full list of indications" for cross-linking, Dr. Seiler said.
"I would like to encourage all of you who do cross-linking of the cornea and who do have a complication, please tell the community," he said.