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Corneal stromal nerve growth may occur post-PRK
Aberrant regeneration of corneal stromal nerves may occur after myopic photorefractive keratectomy re-operation, according to Jay Erie, MD.
Dr. Erie described the case of one patient who underwent bilateral PRK to correct a refractive error of –5.5 D in each eye. More than a year later, the left eye underwent an uncomplicated re-operation to correct a –1 D regression.
Aberrant anterior stromal nerves with a coiled course and irregular branching pattern were identified 22 µm deep to the most anterior keratocyte layer at 1 year after the re-operation in the left eye and remained unchanged for an additional 2 years. No abnormal stromal nerves were identified in the left eye before the re-operation or at any time in the right eye.
The study is published in Cornea.