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Corneal sensitivity not related to corneal nerve morphology
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The morphology of the corneal nerves is not associated with decreased corneal sensitivity in patients with dry eyes, according to a Turkish study.
Researchers at Ankara University evaluated 32 eyes of 16 patients with dry eye (10 of whom had Sjogren’s syndrome) and 19 eyes of 10 age-matched controls to evaluate the corneal sensitivity and nerve morphology in dry eyes. The Cochet-Bonnet esthesiometer was used to study the sensitivity of the central cornea. Corneal nerve morphology was studied with in vivo confocal microscopy.
The mean corneal sensitivity of the patients with dry eye was significantly lower than that of the control group (P < .01). The subepithelial nerves were thicker in dry eyes than in control eyes, but the difference was not statistically significant.
The study is published in Eye.