May 05, 2005
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Corneal ring segments helpful in patients with pellucid marginal degeneration

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FORT LAUDERDALE, Fla. — Intrastromal corneal ring segments were helpful in treating contact lens-intolerant patients with pellucid marginal degeneration, according to a study.

L. DiSilvestre, MD, and colleagues studied the stromal healing response after treatment with Intacs (Addition Technologies) intrastromal corneal ring segments in patients with pellucid marginal degeneration. They described their results in a poster here at the Association for Research in Vision and Ophthalmology meeting.

Before surgery, researchers noted that tomography and confocal microscopy “found normal morphologic features in the central cornea, whereas in peripheral sections, irregular and elongated epithelial cells with altered arrangement of keratocytes were observed.”

Eight eyes of eight contact lens-intolerant patients were implanted with the Intacs segments. Two inserts were placed, one in the superior cornea and one in the inferior cornea. After implantation, researchers said “the stroma in the superior and inferior cornea showed signs of activation (highly reflective nuclei with visible processes) in some of the patients. Around the [segment], moderate fibrosis was detected.”

The authors concluded that the procedure “resulted in efficacy and safety in all patients and provided fast visual rehabilitation.”