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Corneal refractive therapy associated with greater corneal steepening than LASIK
Optom Vis Sci. 2010;87(6):432-439.
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Surgical and non-surgical interventions showed a mid-peripheral local corneal steepening, but the narrower optic zone and higher midperipheral steepening with corneal refractive therapy ostensibly provided the potential for a more relative peripheral myopic increase in corneal power than LASIK, a study showed.
The study authors set out to examine changes in curvature along the horizontal meridian of the anterior cornea taking place after refractive surgery and corneal refractive therapy.
The retrospective study included 122 eyes of 122 patients who had a mean age of 30.6 years. Among the group, 43 patients underwent standard LASIK, 40 had customized LASIK and 39 had corneal refractive therapy in the form of orthokeratology lenses.
Investigators matched patients from different groups to obtain parity in pretreatment refractive error and corneal topographic signatures. Topographic data along the horizontal meridian were collected over a 10-mm corneal diameter and in 1-mm stages using the computer-generated tangential power map.
Study data showed corneal power increasing at the nasal and temporal locations, 2 mm to 3 mm from the corneal keratometric center for corneal refractive therapy and 3 mm to 4 mm from the center for LASIK. The increase was statistically significant (P < .05).
Corneal steepening was more significant after corneal refractive therapy treatment compared with LASIK. However, differences in steepening between LASIK groups were not significant, the authors said.
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