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Corneal inlay, transepithelial cross-linking improved visual results in keratoconus patients
Cornea. 2009;28(7):719-23.
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Patients with keratoconus had improved visual acuity from implantation of a corneal inlay and transepithelial cross-linking treatment, a study found.
"Intacs implantation with transepithelial [cross-linking] is effective in eyes with keratoconus," study authors said. "Collagen cross-linking has an additive effect on Intacs implantation in these eyes and may be considered as an enhancement/stabilizing procedure."
The study looked at 25 eyes of 17 patients with bilateral keratoconus who ranged in age from 16 years to 39 years. Patients underwent implantation of Intacs (Addition Technologies) followed by cross-linking treatment at a mean of 3.98 months. Three-month results were retrospectively reviewed.
After implantation of Intacs, patients had an improvement of 1.9 Snellen lines (P < .05) of uncorrected visual acuity and 1.7 Snellen lines (P < .05) of best corrected visual acuity. After cross-linking, there was a gain of 1.2 additional Snellen lines (P < .05) of UCVA and 0.36 additional Snellen lines (P < .05) of BCVA, study authors said.