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Corneal hysteresis, resistance better measure of IOP after PK

Am J Ophthalmol. 2011;151(5):774-781.

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Corneal hysteresis and corneal resistance may be better predictors of IOP after penetrating keratoplasty than central corneal thickness, a study found.

The consecutive, prospective study evaluated 61 eyes that underwent PK. IOP was measured an average of 65 months after PK with the Goldmann applanation tonometer (Haag-Streit), the Tono-Pen XL (Reichert) and the Ocular Response Analyzer (Reichert). Corneal hysteresis and resistance were measured with the Ocular Response Analyzer.

Researchers found that the IOP measurements derived from the Ocular Response Analyzer (corneal-compensated and Goldmann-correlated) and the Tono-Pen XL correlated significantly with the IOP measurements from the Goldmann applanation tonometer.

Goldmann applanation tonometer IOP was lower than both corneal-compensated IOP (P < .001) and Tono-Pen XL IOP (P = .001). However, Goldmann applanation tonometer IOP did not differ from Goldmann-correlated IOP, the study said.

Central corneal thickness did not correlate to any of the techniques, but regression analysis showed that corneal hysteresis and corneal resistance could play a role in IOP prediction, the study said.