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Corneal hysteresis may be lower in patients with glaucoma
Arch Ophthalmol. 2011;129(4):429-434.
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Patients with glaucoma may demonstrate lower corneal hysteresis compared to control patients, a study found.
The prospective, observational, cross-sectional study included 131 patients with primary angle-closure glaucoma, 162 with primary open-angle glaucoma and 150 healthy controls. All of the patients were Chinese and had no previous intraocular surgery.
One eye of each patient underwent ocular examination including IOP measurement using Goldmann applanation tonometry and the Ocular Response Analyzer (ORA, Reichert).
A lower corneal hysteresis was observed in the two groups of glaucoma patients, with no statistically significant difference between them, compared with the control group. After adjusting for age, sex and IOP measurements by Goldmann applanation tonometry, lower corneal hysteresis persisted only in eyes with primary angle-closure glaucoma.
A majority of the glaucoma patients were on IOP-reducing medications, the effects of which were not assessed, the study authors noted. Additionally, all patients with primary angle-closure glaucoma underwent laser iridotomy, whose influence on ORA measurements remains unknown.