September 10, 2007
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Corneal cross-linking effective without epithelium removal

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STOCKHOLM, Sweden — Corneal cross-linking procedures can be performed without epithelium removal, according to one ophthalmologist speaking here.

Roberto Pinelli, MD, described for attendees of the European Society of Cataract and Refractive Surgeons meeting his results in 30 keratoconic patients treated with corneal collagen cross-linking with no removal of the epithelium.

After following the patients for 6 months, Dr. Pinelli found the mean uncorrected visual acuity improved by 1.3 lines, mean best corrected visual acuity improved by 1.1 lines and there was a mean increase in central pachymetry of 13 µm, according to his results.

Furthermore, the progression of keratoconus stopped in all 30 eyes, and there was a mean decrease in MRSE of –1.27 D, he told the audience.

"These results show that it is not necessary to remove the epithelium to allow the riboflavin to penetrate the cornea," Dr. Pinelli said.